Naltrexone May Soon Treat Heroin Addiction

Recent Norwegian research suggests that naltrexone implants could significantly reduce heroin dependency, which could have an enormous impact on available treatments for heroin addicts. Unlike naltrexone, current treatments for heroin addiction typically involve the use of other addictive morphine-like substances, such as methadone and Subutex.

“Naltrexone is an opioid receptor antagonist used primarily in the management of alcohol dependence and opioid dependence. It is marketed in generic form as its hydrochloride salt, naltrexone hydrochloride, and marketed under the trade names Revia and Depade.”
Researchers studied roughly 56 willing heroin-dependent patients. Twenty-three of the participants had a total of 20 pellets surgically implanted just beneath the skin, which contained naltrexone and a saline solution that allowed for a slow release of the medication to generate a six-month blockage effect.

“The researchers have been using naltrexone, a substance that works by completely blocking the effect of heroin and other morphine substances. This reduces the likelihood of overdose, physical dependency and other drug cravings.”
Participants were studied over a period of six months. Of those implanted with naltrexone, 11 out of 23 were able to abstain from using heroin or other morphine-like substances. In comparison, only 5 out of 26 in the control group were able to avoid using. In addition, the other 12 subjects treated with naltrexone were able to reduce their heroin use by more than half, whereas the remaining 19 subjects in control group continued to use daily.

In addition to these positive statistical results, participants rated this treatment method at 85 out of 100. Addicts and researchers alike can anticipate further studies confirming such positive results and possibly revolutionizing the treatment of heroin addiction some day.

Promising Treatment for Heroin Dependency
Naltrexone

© www.understandingaddictions.com

Non-Habit Forming Painkiller May Soon Hit The Market

Researchers at Stony Brook University have developed a powerful new painkiller that is said to possess no apparent side effects or addictive qualities could be available for purchase within the next year or two. At present, this miracle drug is in Phase II clinical trials in England and Canada.

A painkiller or analgesic is any member of the group of drugs used to relieve pain. The term analgesic is derived from Greek “an”, meaning without, and “algos”, meaning pain. These drugs include paracetamol (better known as acetaminophen), non-steroidal anti-inflammatory drugs (NSAIDs), and opioids such as morphine and opium. Commonly prescribed painkillers include OxyContin, Vicodin, Methadone, Darvocet, Lortab, Lorcet and Percocet, all of which cause dependence.

During the ‘90s, Dr. Simon Halegoua, Professor of Neurobiology & Behavior at Stony Brook and fellow Stony Brook professors Dr. Gail Mandel and Dr. Paul Brehm joined forces to uncover the sodium ion channel, PN1/Nav 1.7, which is involved pain transmission. They predicted that a medication aimed at blocking this specific channel will be capable of controlling pain.
"When a patient is given an opiate like morphine, pain signals are still transmitted from sensory nerves to the central nervous system. Morphine action throughout the brain reduces and alters pain perception, but it also impairs judgement and results in drug dependence," explains Halegoua, also director of the Center for Nervous System Disorders at Stony Brook University. "With drugs targeting the PN1/Nav1.7 sodium ion channel, the pain signals would not be transmitted, even by the sensory nerves. And since the central nervous system is taken out of the equation, there would be no side effects and no addictive qualities."
Relief may be on the horizon, not only for patients suffering with cancer, arthritis, migraine headaches, muscle pain, pain from burns, and pain from other debilitating diseases, but also for those that may be battling addiction as a result of their pain management treatment.

Commonly Prescribed Painkillers:
    Oxycodone
    Brand Names: MS Contin, OxyNorm, Endone, Poladone, Oxycontin
    Street Names: Oxy 80s, oxycotton, oxycet, hillbilly heroin, percs, perks

    Hydrocodone
    Brand Names: Anexisa, Dicodid, Hycodan, Hycomine, Lorcet, Lortab, Norco, Tussionex, Vicodin
    Street Names: pain killer, vikes, hydros

    Propoxyphene
    Brand Name: Darvon
    Street Names: pinks, footballs, pink footballs, 65’s, Ns

    Hydromorphone
    Brand Name: Dilaudid
    Street Names: juice, dillies, drug street heroin

    Meperidine
    Brand Name: Demerol
    Street Names: demmies, pain killer
Some facts and figures:
  • In 2005, roughly 4.7 million people in the US used prescription painkillers for nonmedical reasons.
  • In 2006, roughly 5.2 million people in the US used prescription painkillers for nonmedical reasons, which is nearly twice the estimated number of cocaine users nationwide.
  • In 2007, 2.5 million Americans abused prescription drugs for the first time, compared to 2.1 million who used marijuana for the first time.
  • In 2007, nearly 1 in 5 teens, or 4.5 million kids age 12-19, reportedly abused prescription medications to get high.
  • 1 in 10 US high school seniors admit to abusing prescription painkillers.
  • Almost 50% of teens believe that taking prescription drugs is much safer than using illegal street drugs.
  • Misuse of painkillers represents 3/4 of the overall prescription drug abuse problem.
  • Hydrocodone is the most commonly abused controlled pharmaceutical in the US.
  • In 2007, methadone was found to the cause 785 deaths in Florida alone.
  • Tens of thousands of people are said to be dependent on painkillers, such as Solpadeine and Neurofen Plus, in the UK.
  • Doctors and rehabilitation therapists report that prescription painkiller abuse is one of the most difficult addictions to treat.
A few signs that may suggest painkiller dependency…
    1. Increased usage
    2. Changes in personality
    3. Social withdrawal
    4. Ongoing use
    5. Increased time spent on obtaining prescriptions
    6. Changes in daily habits and appearance
    7. Neglected responsibilities
    8. Increased sensitivity
    9. Blackouts and forgetfulness
    10. Defensiveness
Powerful New Painkiller With No Apparent Side Effects or Addictive Qualities, May Be Ready in a Year
Analgesic
Foundation For A Drug-Free World
A Familiar Fiend: Painkiller Addiction

© www.understandingaddictions.com

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